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Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA
The treatment or prevention of bleeding in patients with hemophilia A relies on replacement therapy with different factor VIII (FVIII)-containing products or on the use of by-passing agents, i.e., activated prothrombin complex concentrates or recombinant activated factor VII. Emerging approaches inc...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109737/ https://www.ncbi.nlm.nih.gov/pubmed/31289204 http://dx.doi.org/10.3324/haematol.2018.210583 |