Methotrexate-associated toxicity in children with Down syndrome and acute lymphoblastic leukemia during consolidation therapy with high dose methotrexate according to ALL-BFM treatment regimen

Children with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) often suffer from severe toxicities during treatment, especially with high-dose methotrexate (HD-MTX). Systematic data on methotrexate (MTX) toxicity in these patients are rare. We analyzed seven MTX-associated toxicities during...

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Detalles Bibliográficos
Autores principales: Kroll, Mirko, Kaupat-Bleckmann, Kirsten, Mörickel, Anja, Altenl, Julia, Schewel, Denis M., Stanullal, Martin, Zimmermann, Martin, Schrappe, Martin, Cario, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109740/
https://www.ncbi.nlm.nih.gov/pubmed/31371414
http://dx.doi.org/10.3324/haematol.2019.224774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109740/
https://www.ncbi.nlm.nih.gov/pubmed/31371414
http://dx.doi.org/10.3324/haematol.2019.224774

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