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Methotrexate-associated toxicity in children with Down syndrome and acute lymphoblastic leukemia during consolidation therapy with high dose methotrexate according to ALL-BFM treatment regimen

Children with Down syndrome (DS) and acute lymphoblastic leukemia (ALL) often suffer from severe toxicities during treatment, especially with high-dose methotrexate (HD-MTX). Systematic data on methotrexate (MTX) toxicity in these patients are rare. We analyzed seven MTX-associated toxicities during...

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Detalles Bibliográficos
Autores principales:	Kroll, Mirko, Kaupat-Bleckmann, Kirsten, Mörickel, Anja, Altenl, Julia, Schewel, Denis M., Stanullal, Martin, Zimmermann, Martin, Schrappe, Martin, Cario, Gunnar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109740/ https://www.ncbi.nlm.nih.gov/pubmed/31371414 http://dx.doi.org/10.3324/haematol.2019.224774

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