Histone-induced thrombotic thrombocytopenic purpura in adamts13(−/−) zebrafish depends on von Willebrand factor

Thrombotic thrombocytopenic purpura (TTP) is caused by severe deficiency of ADAMTS13 (A13), a plasma metalloprotease that cleaves endothelium-derived von Willebrand factor (VWF). However, severe A13 deficiency alone is often not sufficient to cause an acute TTP; additional factors may be required to...

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Detalles Bibliográficos
Autores principales: Zheng, Liang, Abdelgawwad, Mohammad S., Zhang, Di, Xu, Leimeng, Wei, Shi, Cao, Wenjing, Zheng, X. Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109750/
https://www.ncbi.nlm.nih.gov/pubmed/31753928
http://dx.doi.org/10.3324/haematol.2019.237396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109750/
https://www.ncbi.nlm.nih.gov/pubmed/31753928
http://dx.doi.org/10.3324/haematol.2019.237396

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