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Predicting proteolytic sites in extracellular proteins: only halfway there

Motivation: Many secretory proteins are synthesized as inactive precursors that must undergo post-translational proteolysis in order to mature and become active. In the current study, we address the challenge of sequence-based discovery of proteolytic sites in secreted proteins using machine learnin...

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Detalles Bibliográficos
Autores principales: Kliger, Yossef, Gofer, Eyal, Wool, Assaf, Toporik, Amir, Apatoff, Avihay, Olshansky, Moshe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109841/
https://www.ncbi.nlm.nih.gov/pubmed/18321887
http://dx.doi.org/10.1093/bioinformatics/btn084