Molecular flexibility of DNA as a key determinant of RAD51 recruitment

The timely activation of homologous recombination is essential for the maintenance of genome stability, in which the RAD51 recombinase plays a central role. Biochemically, human RAD51 polymerises faster on single‐stranded DNA (ssDNA) compared to double‐stranded DNA (dsDNA), raising a key conceptual...

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Detalles Bibliográficos
Autores principales: Paoletti, Federico, El‐Sagheer, Afaf H, Allard, Jun, Brown, Tom, Dushek, Omer, Esashi, Fumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110135/
https://www.ncbi.nlm.nih.gov/pubmed/31943278
http://dx.doi.org/10.15252/embj.2019103002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110135/
https://www.ncbi.nlm.nih.gov/pubmed/31943278
http://dx.doi.org/10.15252/embj.2019103002

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