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Covariate-constrained randomization for cluster randomized trials in the long-term care setting: Application to the TRAIN-AD trial

Little has been reported on strategies to ensure key covariate balance in cluster randomized trials in the nursing home setting. Facilities vary widely on key characteristics, small numbers may be randomized, and staggered enrollment is often necessary. A covariate-constrained algorithm was used to...

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Detalles Bibliográficos
Autores principales: Shaffer, Michele L., D'Agata, Erika M.C., Habtemariam, Daniel, Mitchell, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110330/
https://www.ncbi.nlm.nih.gov/pubmed/32258819
http://dx.doi.org/10.1016/j.conctc.2020.100558