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The macro domain protein family: Structure, functions, and their potential therapeutic implications

Macro domains are ancient, highly evolutionarily conserved domains that are widely distributed throughout all kingdoms of life. The ‘macro fold’ is roughly 25 kDa in size and is composed of a mixed α–β fold with similarity to the P loop-containing nucleotide triphosphate hydrolases. They function as...

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Detalles Bibliográficos
Autores principales: Han, Weidong, Li, Xiaolei, Fu, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110529/
https://www.ncbi.nlm.nih.gov/pubmed/21421074
http://dx.doi.org/10.1016/j.mrrev.2011.03.001