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Dafachronic acid and temperature regulate canonical dauer pathways during Nippostrongylus brasiliensis infectious larvae activation

BACKGROUND: While immune responses to the murine hookworm Nippostrongylus brasiliensis have been investigated, signaling pathways regulating development of infectious larvae (iL3) are not well understood. We hypothesized that N. brasiliensis would use pathways similar to those controlling dauer deve...

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Detalles Bibliográficos
Autores principales: Ayoade, Katherine Omueti, Carranza, Faith R., Cho, Woong Hee, Wang, Zhu, Kliewer, Steven A., Mangelsdorf, David J., Stoltzfus, Jonathan D. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110753/
https://www.ncbi.nlm.nih.gov/pubmed/32238181
http://dx.doi.org/10.1186/s13071-020-04035-z