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Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood–brain barrier inducer

BACKGROUND: Several secreted factors have been identified as drivers of cerebral vasculature development and inducers of blood–brain barrier (BBB) differentiation. Vascular endothelial growth factor A (VEGF-A) is central for driving cerebral angiogenesis and Wnt family factors (Wnt7a, Wnt7b and norr...

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Detalles Bibliográficos
Autores principales: Bar, Ofri, Gelb, Sivan, Atamny, Kian, Anzi, Shira, Ben-Zvi, Ayal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110827/
https://www.ncbi.nlm.nih.gov/pubmed/32238174
http://dx.doi.org/10.1186/s12987-020-00188-2