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Hypoxia-induced complement dysregulation is associated with microvascular impairments in mouse tracheal transplants

BACKGROUND: Complement Regulatory Proteins (CRPs), especially CD55 primarily negate complement factor 3-mediated injuries and maintain tissue homeostasis during complement cascade activation. Complement activation and regulation during alloimmune inflammation contribute to allograft injury and there...

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Detalles Bibliográficos
Autores principales: Khan, Mohammad Afzal, Shamma, Talal, Kazmi, Shadab, Altuhami, Abdullah, Ahmed, Hala Abdalrahman, Assiri, Abdullah Mohammed, Broering, Dieter Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110829/
https://www.ncbi.nlm.nih.gov/pubmed/32234039
http://dx.doi.org/10.1186/s12967-020-02305-z