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Hypoxia-induced complement dysregulation is associated with microvascular impairments in mouse tracheal transplants
BACKGROUND: Complement Regulatory Proteins (CRPs), especially CD55 primarily negate complement factor 3-mediated injuries and maintain tissue homeostasis during complement cascade activation. Complement activation and regulation during alloimmune inflammation contribute to allograft injury and there...
Autores principales: | Khan, Mohammad Afzal, Shamma, Talal, Kazmi, Shadab, Altuhami, Abdullah, Ahmed, Hala Abdalrahman, Assiri, Abdullah Mohammed, Broering, Dieter Clemens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110829/ https://www.ncbi.nlm.nih.gov/pubmed/32234039 http://dx.doi.org/10.1186/s12967-020-02305-z |
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