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Extraordinary GU-rich single-strand RNA identified from SARS coronavirus contributes an excessive innate immune response

A dangerous cytokine storm occurs in the SARS involving in immune disorder, but many aspects of the pathogenetic mechanism remain obscure since its outbreak. To deeply reveal the interaction of host and SARS-CoV, based on the basic structural feature of pathogen-associated molecular pattern, we crea...

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Detalles Bibliográficos
Autores principales: Li, Yan, Chen, Ming, Cao, Hongwei, Zhu, Yuanfeng, Zheng, Jiang, Zhou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institut Pasteur. Published by Elsevier Masson SAS 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110875/
https://www.ncbi.nlm.nih.gov/pubmed/23123977
http://dx.doi.org/10.1016/j.micinf.2012.10.008