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SARS coronavirus 8b reduces viral replication by down-regulating E via an ubiquitin-independent proteasome pathway

The severe acute respiratory syndrome coronavirus (SARS-CoV) 8b protein, which is not expressed by other known coronaviruses, can down-regulate the envelope (E) protein via a proteasome-dependent pathway. Here, we showed that the down-regulation of E is not dependent on the lysine residues on 8b and...

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Detalles Bibliográficos
Autores principales: Keng, Choong-Tat, Åkerström, Sara, Leung, Cynthia Sau-Wai, Poon, Leo L.M., Peiris, J.S. Malik, Mirazimi, Ali, Tan, Yee-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institut Pasteur. Published by Elsevier Masson SAS 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110893/
https://www.ncbi.nlm.nih.gov/pubmed/21035562
http://dx.doi.org/10.1016/j.micinf.2010.10.017