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Investigation of the immunogenicity of Zika glycan loop

BACKGROUND: Zika virus (ZIKV) is a major human pathogen and member of the Flavivirus genus. Previous studies have identified neutralizing antibodies from Zika patients that bind to quaternary epitopes across neighboring envelope (E) proteins, called E dimer epitopes (EDE). An asparagine-linked glyca...

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Detalles Bibliográficos
Autores principales: Henderson, Elizabeth A., Tam, Christina C., Cheng, Luisa W., Ngono, Annie Elong, Nguyen, Anh-Viet, Shresta, Sujan, McGee, Matt, Padgett, Hal, Grill, Laurence K., Martchenko Shilman, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7110905/
https://www.ncbi.nlm.nih.gov/pubmed/32234060
http://dx.doi.org/10.1186/s12985-020-01313-1