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Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein
Heptad repeat regions (HR1 and HR2) are highly conserved sequences located in the glycoproteins of enveloped viruses. They form a six-helix bundle structure and are important in the process of virus fusion. Peptides derived from the HR regions of some viruses have been shown to inhibit the entry of...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111000/ https://www.ncbi.nlm.nih.gov/pubmed/15184046 http://dx.doi.org/10.1016/j.bbrc.2004.05.046 |