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Suppression of SARS-CoV entry by peptides corresponding to heptad regions on spike glycoprotein

Heptad repeat regions (HR1 and HR2) are highly conserved sequences located in the glycoproteins of enveloped viruses. They form a six-helix bundle structure and are important in the process of virus fusion. Peptides derived from the HR regions of some viruses have been shown to inhibit the entry of...

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Detalles Bibliográficos
Autores principales: Yuan, Kehu, Yi, Ling, Chen, Jian, Qu, Xiuxia, Qing, Tingting, Rao, Xi, Jiang, Pengfei, Hu, Jianhe, Xiong, Zikai, Nie, Yuchun, Shi, Xuanling, Wang, Wei, Ling, Chen, Yin, Xiaolei, Fan, Keqiang, Lai, Luhua, Ding, Mingxiao, Deng, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111000/
https://www.ncbi.nlm.nih.gov/pubmed/15184046
http://dx.doi.org/10.1016/j.bbrc.2004.05.046