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Characterization of humoral responses in mice immunized with plasmid DNAs encoding SARS-CoV spike gene fragments
The immunological characteristics of SARS-CoV spike protein were investigated by administering mice with plasmids encoding various S gene fragments. We showed that the secreting forms of S1, S2 subunits and the N-terminus of S1 subunit (residues 18–495) were capable of eliciting SARS-CoV specific an...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111006/ https://www.ncbi.nlm.nih.gov/pubmed/14985131 http://dx.doi.org/10.1016/j.bbrc.2004.01.166 |