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Characterization of humoral responses in mice immunized with plasmid DNAs encoding SARS-CoV spike gene fragments

The immunological characteristics of SARS-CoV spike protein were investigated by administering mice with plasmids encoding various S gene fragments. We showed that the secreting forms of S1, S2 subunits and the N-terminus of S1 subunit (residues 18–495) were capable of eliciting SARS-CoV specific an...

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Detalles Bibliográficos
Autores principales: Zeng, Fanya, Chow, Ken Yan Ching, Hon, Chung Chau, Law, Ka Man, Yip, Chi Wai, Chan, Kwok Hung, Peiris, Joseph S.Malik, Leung, Frederick Chi Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111006/
https://www.ncbi.nlm.nih.gov/pubmed/14985131
http://dx.doi.org/10.1016/j.bbrc.2004.01.166