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Prohibitin Ligands in Cell Death and Survival: Mode of Action and Therapeutic Potential

Prohibitins (PHBs) are scaffold proteins that modulate many signaling pathways controlling cell survival, metabolism, and inflammation. Several drugs that target PHBs have been identified and evaluated for various clinical applications. Preclinical and clinical studies indicate that these PHB ligand...

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Detalles Bibliográficos
Autores principales: Thuaud, Frédéric, Ribeiro, Nigel, Nebigil, Canan G., Désaubry, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111013/
https://www.ncbi.nlm.nih.gov/pubmed/23521790
http://dx.doi.org/10.1016/j.chembiol.2013.02.006