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Prohibitin Ligands in Cell Death and Survival: Mode of Action and Therapeutic Potential
Prohibitins (PHBs) are scaffold proteins that modulate many signaling pathways controlling cell survival, metabolism, and inflammation. Several drugs that target PHBs have been identified and evaluated for various clinical applications. Preclinical and clinical studies indicate that these PHB ligand...
Autores principales: | Thuaud, Frédéric, Ribeiro, Nigel, Nebigil, Canan G., Désaubry, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111013/ https://www.ncbi.nlm.nih.gov/pubmed/23521790 http://dx.doi.org/10.1016/j.chembiol.2013.02.006 |
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