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Structures of T Cell Immunoglobulin Mucin Receptors 1 and 2 Reveal Mechanisms for Regulation of Immune Responses by the TIM Receptor Family

The T cell immunoglobulin mucin (TIM) receptors are involved in the regulation of immune responses, autoimmunity, and allergy. Structures of the N-terminal ligand binding domain of the murine mTIM-1 and mTIM-2 receptors revealed an immunoglobulin (Ig) fold, with four Cys residues bridging a distinct...

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Detalles Bibliográficos
Autores principales: Santiago, César, Ballesteros, Angela, Tami, Cecilia, Martínez-Muñoz, Laura, Kaplan, Gerardo G., Casasnovas, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111020/
https://www.ncbi.nlm.nih.gov/pubmed/17363299
http://dx.doi.org/10.1016/j.immuni.2007.01.014