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Regulation of astrocyte proliferation by prostaglandin E(2) and the α subtype of protein kinase C

We found that astrocytes expressed the α subtype of protein kinase C. Treatment with12-O-tetradecanoylphorbol 13-acetate (TPA) caused cultured astrocytes to proliferate. This effect of TPA was blocked by staurosporine, a potent protein kinase C inhibitor, suggesting the involvement of protein kinase...

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Detalles Bibliográficos
Autores principales: Sawada, Makoto, Suzumura, Akio, Ohno, Kazushige, Marunouchi, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111161/
https://www.ncbi.nlm.nih.gov/pubmed/8348305
http://dx.doi.org/10.1016/0006-8993(93)90455-V