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Expression cloning of functional receptor used by SARS coronavirus

We have expressed a series of truncated spike (S) glycoproteins of SARS-CoV and found that the N-terminus 14–502 residuals were sufficient to bind to SARS-CoV susceptible Vero E6 cells. With this soluble S protein fragment as an affinity ligand, we screened HeLa cells transduced with retroviral cDNA...

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Detalles Bibliográficos
Autores principales: Wang, Peigang, Chen, Jian, Zheng, Aihua, Nie, Yuchun, Shi, Xuanling, Wang, Wei, Wang, Guangwen, Luo, Min, Liu, Huijun, Tan, Lei, Song, Xijun, Wang, Zai, Yin, Xiaolei, Qu, Xiuxia, Wang, Xiaojing, Qing, Tingting, Ding, Mingxiao, Deng, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111169/
https://www.ncbi.nlm.nih.gov/pubmed/14766227
http://dx.doi.org/10.1016/j.bbrc.2004.01.076