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IκB kinase ɛ (IKKɛ): A therapeutic target in inflammation and cancer
The innate immune system forms our first line of defense against invading pathogens and relies for a major part on the activation of two transcription factors, NF-κB and IRF3. Signaling pathways that activate these transcription factors are intertwined at the level of the canonical IκB kinases (IKKα...
Autores principales: | Verhelst, Kelly, Verstrepen, Lynn, Carpentier, Isabelle, Beyaert, Rudi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111187/ https://www.ncbi.nlm.nih.gov/pubmed/23333767 http://dx.doi.org/10.1016/j.bcp.2013.01.007 |
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