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The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation

Obesity-induced diabetes affects >400 million people worldwide. Uncontrolled lipolysis (free fatty acid release from adipocytes) can contribute to diabetes and obesity. To identify future therapeutic avenues targeting this pathway, we performed a high-throughput screen and identified the extracel...

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Detalles Bibliográficos
Autores principales: El-Merahbi, Rabih, Viera, Jonathan Trujillo, Valdes, Angel Loza, Kolczynska, Katarzyna, Reuter, Saskia, Löffler, Mona C., Erk, Manuela, Ade, Carsten P., Karwen, Till, Mayer, Alexander E., Eilers, Martin, Sumara, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111262/
https://www.ncbi.nlm.nih.gov/pubmed/32139423
http://dx.doi.org/10.1101/gad.333617.119