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Structural basis for the dimerization and substrate recognition specificity of porcine epidemic diarrhea virus 3C-like protease

Porcine epidemic diarrhea virus (PEDV), a member of the genus Alphacoronavirus, has caused significant damage to the Asian and American pork industries. Coronavirus 3C-like protease (3CL(pro)), which is involved in the processing of viral polyproteins for viral replication, is an appealing antiviral...

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Detalles Bibliográficos
Autores principales: Ye, Gang, Deng, Feng, Shen, Zhou, Luo, Rui, Zhao, Ling, Xiao, Shaobo, Fu, Zhen F., Peng, Guiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111274/
https://www.ncbi.nlm.nih.gov/pubmed/27128350
http://dx.doi.org/10.1016/j.virol.2016.04.018