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Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1

Filoviruses, including Ebola and Marburg, cause fatal hemorrhagic fever in humans and primates. Understanding how these viruses enter host cells could help to develop effective therapeutics. An endosomal protein, Niemann-Pick C1 (NPC1), has been identified as a necessary entry receptor for this proc...

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Detalles Bibliográficos
Autores principales: Wang, Han, Shi, Yi, Song, Jian, Qi, Jianxun, Lu, Guangwen, Yan, Jinghua, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111281/
https://www.ncbi.nlm.nih.gov/pubmed/26771495
http://dx.doi.org/10.1016/j.cell.2015.12.044