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Protection against infectious bronchitis virus by spike ectodomain subunit vaccine

The avian coronavirus infectious bronchitis virus (IBV) S1 subunit of the spike (S) glycoprotein mediates viral attachment to host cells and the S2 subunit is responsible for membrane fusion. Using IBV Arkansas-type (Ark) S protein histochemistry, we show that extension of S1 with the S2 ectodomain...

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Detalles Bibliográficos
Autores principales: Eldemery, Fatma, Joiner, Kellye S., Toro, Haroldo, van Santen, Vicky L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111290/
https://www.ncbi.nlm.nih.gov/pubmed/28899630
http://dx.doi.org/10.1016/j.vaccine.2017.09.013