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Advax augments B and T cell responses upon influenza vaccination via the respiratory tract and enables complete protection of mice against lethal influenza virus challenge

Administration of influenza vaccines via the respiratory tract has potential benefits over conventional parenteral administration, inducing immunity directly at the site of influenza exposure as well as being needle free. In this study, we investigated the suitability of Advax™, a stable particulate...

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Detalles Bibliográficos
Autores principales: Tomar, Jasmine, Patil, Harshad P., Bracho, Gustavo, Tonnis, Wouter F., Frijlink, Henderik W., Petrovsky, Nikolai, Vanbever, Rita, Huckriede, Anke, Hinrichs, Wouter L.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111335/
https://www.ncbi.nlm.nih.gov/pubmed/30218687
http://dx.doi.org/10.1016/j.jconrel.2018.09.006