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Inhibition of NF-κB activity by the porcine epidemic diarrhea virus nonstructural protein 1 for innate immune evasion

Porcine epidemic diarrhea virus emerged in the US is known to suppress the type I interferons response during infection. In the present study using porcine epithelial cells, we showed that PEDV inhibited both NF-κB and proinflammatory cytokines. PEDV blocked the p65 activation in infected cells and...

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Detalles Bibliográficos
Autores principales: Zhang, Qingzhan, Ma, Jinyou, Yoo, Dongwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111422/
https://www.ncbi.nlm.nih.gov/pubmed/28715653
http://dx.doi.org/10.1016/j.virol.2017.07.009