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Decreased expression of type I (IFN-β) and type III (IFN-λ) interferons and interferon-stimulated genes in patients with chronic rhinosinusitis with and without nasal polyps

BACKGROUND: Little is known about antiviral responses in the sinonasal mucosal tissue of patients with chronic rhinosinusitis (CRS). OBJECTIVE: we investigated the presence of virus and the expression of Toll-like receptor (TLR) 3, TLR7, and interferon and interferon-stimulated genes (ISGs) in healt...

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Detalles Bibliográficos
Autores principales: Hwang, Jae Woong, Lee, Ki Jeong, Choi, In Hak, Han, Hye Min, Kim, Tae Hoon, Lee, Sang Hag
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Academy of Allergy, Asthma & Immunology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111475/
https://www.ncbi.nlm.nih.gov/pubmed/31449915
http://dx.doi.org/10.1016/j.jaci.2019.08.010