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Identification of a clinical compound losmapimod that blocks Lassa virus entry

Lassa virus (LASV) causes Lassa hemorrhagic fever in humans and poses a significant threat to public health in West Africa. Current therapeutic treatments for Lassa fever are limited, making the development of novel countermeasures an urgent priority. In this study, we identified losmapimod, a p38 m...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyu, Yan, Feihu, Tang, Ke, Chen, Qing, Guo, Jiamei, Zhu, Wenjun, He, Shihua, Banadyga, Logan, Qiu, Xiangguo, Guo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111477/
https://www.ncbi.nlm.nih.gov/pubmed/30953674
http://dx.doi.org/10.1016/j.antiviral.2019.03.014