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Identification of FMR1-regulated molecular networks in human neurodevelopment

RNA-binding proteins (RNA-BPs) play critical roles in development and disease to regulate gene expression. However, genome-wide identification of their targets in primary human cells has been challenging. Here, we applied a modified CLIP-seq strategy to identify genome-wide targets of the FMRP trans...

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Detalles Bibliográficos
Autores principales: Li, Meng, Shin, Junha, Risgaard, Ryan D., Parries, Molly J., Wang, Jianyi, Chasman, Deborah, Liu, Shuang, Roy, Sushmita, Bhattacharyya, Anita, Zhao, Xinyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111522/
https://www.ncbi.nlm.nih.gov/pubmed/32179589
http://dx.doi.org/10.1101/gr.251405.119