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Structure of the S1 subunit C-terminal domain from bat-derived coronavirus HKU5 spike protein

Accumulating evidence indicates that MERS-CoV originated from bat coronaviruses (BatCoVs). Previously, we demonstrated that both MERS-CoV and BatCoV HKU4 use CD26 as a receptor, but how the BatCoVs evolved to bind CD26 is an intriguing question. Here, we solved the crystal structure of the S1 subuni...

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Detalles Bibliográficos
Autores principales: Han, Xue, Qi, Jianxun, Song, Hao, Wang, Qihui, Zhang, Yanfang, Wu, Ying, Lu, Guangwen, Yuen, Kwok-Yung, Shi, Yi, Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111649/
https://www.ncbi.nlm.nih.gov/pubmed/28432925
http://dx.doi.org/10.1016/j.virol.2017.04.016