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Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO

Porcine deltacoronavirus (PDCoV) causes acute enteric disease and mortality in seronegative neonatal piglets. Previously we have demonstrated that PDCoV infection suppresses the production of interferon-beta (IFN-β), while the detailed mechanisms are poorly understood. Here, we demonstrate that nons...

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Detalles Bibliográficos
Autores principales: Zhu, Xinyu, Fang, Liurong, Wang, Dang, Yang, Yuting, Chen, Jiyao, Ye, Xu, Foda, Mohamed Frahat, Xiao, Shaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111669/
https://www.ncbi.nlm.nih.gov/pubmed/27984784
http://dx.doi.org/10.1016/j.virol.2016.12.005