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The S2 glycoprotein subunit of porcine epidemic diarrhea virus contains immunodominant neutralizing epitopes

The porcine epidemic diarrhea virus (PEDV) spike (S) protein is the major target of neutralizing antibodies against PEDV. Here immunodominant neutralizing epitopes of PEDV were identified using a panel of S-specific monoclonal antibodies (mAbs). Ten of eleven S-specific mAbs successfully neutralized...

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Detalles Bibliográficos
Autores principales: Okda, Faten A., Lawson, Steven, Singrey, Aaron, Nelson, Julie, Hain, Kyle S., Joshi, Lok R., Christopher-Hennings, Jane, Nelson, Eric A., Diel, Diego G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111671/
https://www.ncbi.nlm.nih.gov/pubmed/28647506
http://dx.doi.org/10.1016/j.virol.2017.06.013