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Two-amino acids change in the nsp4 of SARS coronavirus abolishes viral replication
Infection with coronavirus rearranges the host cell membrane to assemble a replication/transcription complex in which replication of the viral genome and transcription of viral mRNA occur. Although coexistence of nsp3 and nsp4 is known to cause membrane rearrangement, the mechanisms underlying the i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111695/ https://www.ncbi.nlm.nih.gov/pubmed/28738245 http://dx.doi.org/10.1016/j.virol.2017.07.019 |