Substitutions of conserved amino acids in the receptor-binding domain of the spike glycoprotein affect utilization of murine CEACAM1a by the murine coronavirus MHV-A59

The host range of the murine coronavirus (MHV) is limited to susceptible mice and murine cell lines by interactions of the spike glycoprotein (S) with its receptor, mCEACAM1a. We identified five residues in S (S33, L79, T82, Y162 and K183) that are conserved in the receptor-binding domain of MHV str...

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Detalles Bibliográficos
Autores principales: Thackray, Larissa B., Turner, Brian C., Holmes, Kathryn V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111733/
https://www.ncbi.nlm.nih.gov/pubmed/15749126
http://dx.doi.org/10.1016/j.virol.2005.01.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111733/
https://www.ncbi.nlm.nih.gov/pubmed/15749126
http://dx.doi.org/10.1016/j.virol.2005.01.016

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