Cargando…

Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell–cell fusion but does not affect virion entry

The fusogenic potential of Class I viral envelope glycoproteins is activated by proteloytic cleavage of the precursor glycoprotein to generate the mature receptor-binding and transmembrane fusion subunits. Although the coronavirus (CoV) S glycoproteins share membership in this class of envelope glyc...

Descripción completa

Detalles Bibliográficos
Autores principales: Follis, Kathryn E., York, Joanne, Nunberg, Jack H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111780/
https://www.ncbi.nlm.nih.gov/pubmed/16519916
http://dx.doi.org/10.1016/j.virol.2006.02.003