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Use of chiral-pool approach into epi-thieno analogues of the scarce bioactive phenanthroquinolizidine alkaloids
The stereoselective synthesis of epi-thieno analogues of the phenanthroquinolizidine bioactive alkaloids (−)-Cryptopleurine and (−)-(15R)-Hydroxycryptopleurine was achieved in five steps starting from easily available enantiopure (S)-2-aminoadipic acid used as chiral pool and nitrogen atom source. D...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Ltd.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111795/ https://www.ncbi.nlm.nih.gov/pubmed/32287429 http://dx.doi.org/10.1016/j.tet.2016.04.047 |