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Use of chiral-pool approach into epi-thieno analogues of the scarce bioactive phenanthroquinolizidine alkaloids

The stereoselective synthesis of epi-thieno analogues of the phenanthroquinolizidine bioactive alkaloids (−)-Cryptopleurine and (−)-(15R)-Hydroxycryptopleurine was achieved in five steps starting from easily available enantiopure (S)-2-aminoadipic acid used as chiral pool and nitrogen atom source. D...

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Detalles Bibliográficos
Autores principales:	Šafář, Peter, Marchalín, Štefan, Prónayová, Nadežda, Vrábel, Viktor, Lawson, Ata Martin, Othman, Mohamed, Daïch, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier Ltd. 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111795/ https://www.ncbi.nlm.nih.gov/pubmed/32287429 http://dx.doi.org/10.1016/j.tet.2016.04.047

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