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Impact of polymorphisms in the DC-SIGNR neck domain on the interaction with pathogens

The lectins DC-SIGN and DC-SIGNR augment infection by human immunodeficiency virus (HIV), Ebolavirus (EBOV) and other pathogens. The neck domain of these proteins drives multimerization, which is believed to be required for efficient recognition of multivalent ligands. The neck domain of DC-SIGN con...

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Detalles Bibliográficos
Autores principales: Gramberg, Thomas, Zhu, Tuofu, Chaipan, Chawaree, Marzi, Andrea, Liu, Huanliang, Wegele, Anja, Andrus, Thomas, Hofmann, Heike, Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111803/
https://www.ncbi.nlm.nih.gov/pubmed/16413044
http://dx.doi.org/10.1016/j.virol.2005.11.033