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Evidence that multiple defects in murine DC-SIGN inhibit a functional interaction with pathogens

Certain viruses, bacteria, fungi and parasites target dendritic cells through the interaction with the cellular attachment factor DC-SIGN, making this C-type lectin an attractive target for therapeutic intervention. Studies on DC-SIGN function would be greatly aided by the establishment of a mouse m...

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Detalles Bibliográficos
Autores principales: Gramberg, Thomas, Caminschi, Irina, Wegele, Anja, Hofmann, Heike, Pöhlmann, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111805/
https://www.ncbi.nlm.nih.gov/pubmed/16297949
http://dx.doi.org/10.1016/j.virol.2005.10.008