Neutralizing antibody and protective immunity to SARS coronavirus infection of mice induced by a soluble recombinant polypeptide containing an N-terminal segment of the spike glycoprotein

A secreted, glycosylated polypeptide containing amino acids 14 to 762 of the SARS coronavirus (SARS-CoV) spike protein and a polyhistidine tag was expressed in recombinant baculovirus-infected insect cells. Mice received the affinity-purified protein with either a saponin (QS21) or a Ribi (MPL + TDM...

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Detalles Bibliográficos
Autores principales: Bisht, Himani, Roberts, Anjeanette, Vogel, Leatrice, Subbarao, Kanta, Moss, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111832/
https://www.ncbi.nlm.nih.gov/pubmed/15780866
http://dx.doi.org/10.1016/j.virol.2005.01.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111832/
https://www.ncbi.nlm.nih.gov/pubmed/15780866
http://dx.doi.org/10.1016/j.virol.2005.01.042

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