Cargando…
A regioselective etherification of pyridoxine via an ortho-pyridinone methide intermediate
The catalyst-free, regioselective synthesis of 4′-O-substituted pyridoxine derivatives under solventless conditions is described. The methodology relies on the highly regioselective formation of the ortho-pyridinone methide from pyridoxine and subsequent oxa-Michael addition of alcohol nucleophiles....
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111860/ https://www.ncbi.nlm.nih.gov/pubmed/32287448 http://dx.doi.org/10.1016/j.tetlet.2017.04.082 |