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Programmed ribosomal frameshifting in decoding the SARS-CoV genome

Programmed ribosomal frameshifting is an essential mechanism used for the expression of orf1b in coronaviruses. Comparative analysis of the frameshift region reveals a universal shift site U_UUA_AAC, followed by a predicted downstream RNA structure in the form of either a pseudoknot or kissing stem...

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Detalles Bibliográficos
Autores principales: Baranov, Pavel V., Henderson, Clark M., Anderson, Christine B., Gesteland, Raymond F., Atkins, John F., Howard, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111862/
https://www.ncbi.nlm.nih.gov/pubmed/15680415
http://dx.doi.org/10.1016/j.virol.2004.11.038