Identification of critical determinants on ACE2 for SARS-CoV entry and development of a potent entry inhibitor

Severe acute respiratory syndrome (SARS) is caused by a novel coronavirus, SARS-CoV. Virus entry into cells is mediated through interactions between spike (S) glycoprotein and angiotensin-converting enzyme 2 (ACE2). Alanine scanning mutagenesis analysis was performed to identify determinants on ACE2...

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Detalles Bibliográficos
Autores principales: Han, Dong P., Penn-Nicholson, Adam, Cho, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111894/
https://www.ncbi.nlm.nih.gov/pubmed/16510163
http://dx.doi.org/10.1016/j.virol.2006.01.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111894/
https://www.ncbi.nlm.nih.gov/pubmed/16510163
http://dx.doi.org/10.1016/j.virol.2006.01.029

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