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Translation of viral mRNAs that do not require eIF4E is blocked by the inhibitor 4EGI-1
High throughput screening has rendered new inhibitors of eukaryotic protein synthesis. One such molecule, 4EGI-1 has been reported to selectively block the initiation factor eIF4E. We have investigated the action of this inhibitor on translation directed by several viral mRNAs which, in principle, d...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111898/ https://www.ncbi.nlm.nih.gov/pubmed/23870416 http://dx.doi.org/10.1016/j.virol.2013.06.008 |