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Phage displayed peptides recognizing porcine aminopeptidase N inhibit transmissible gastroenteritis coronavirus infection in vitro

Porcine aminopeptidase N (pAPN) is a cellular receptor of transmissible gastroenteritis virus (TGEV), a porcine coronavirus. Interaction between the spike (S) protein of TGEV and pAPN initiates cell infection. Small molecules, especially peptides are an expanding area for therapy or diagnostic assay...

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Detalles Bibliográficos
Autores principales: Ren, Xiaofeng, Liu, Boqi, Yin, Jiechao, Zhang, Heng, Li, Guangxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111919/
https://www.ncbi.nlm.nih.gov/pubmed/21176936
http://dx.doi.org/10.1016/j.virol.2010.11.014