Interferon-γ and interleukin-4 downregulate expression of the SARS coronavirus receptor ACE2 in Vero E6 cells

Interferons (IFNs) inhibit severe acute respiratory syndrome coronavirus (SARS-CoV) replication and might be valuable for SARS treatment. In this study, we demonstrate that treatment of Vero E6 cells with interleukin-4 (IL-4) decreased the susceptibility of these cells to SARS-CoV infection. In cont...

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Detalles Bibliográficos
Autores principales: de Lang, Anna, Osterhaus, Albert D.M.E, Haagmans, Bart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111939/
https://www.ncbi.nlm.nih.gov/pubmed/16860835
http://dx.doi.org/10.1016/j.virol.2006.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111939/
https://www.ncbi.nlm.nih.gov/pubmed/16860835
http://dx.doi.org/10.1016/j.virol.2006.06.011

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