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Replacement of the heterologous 5(′) untranslated region allows preservation of the fully functional activities of type 2 porcine reproductive and respiratory syndrome virus

The 5′ untranslated region (UTR) is believed to be vital for the replication of porcine reproductive and respiratory syndrome virus (PRRSV), yet its functional mechanism remains largely unknown. In this study, to define the cis-acting elements for viral replication and infectivity, The 5′ UTR swappi...

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Detalles Bibliográficos
Autores principales: Gao, Fei, Yao, Huochun, Lu, Jiaqi, Wei, Zuzhang, Zheng, Haihong, Zhuang, Jinshan, Tong, Guangzhi, Yuan, Shishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111940/
https://www.ncbi.nlm.nih.gov/pubmed/23453581
http://dx.doi.org/10.1016/j.virol.2012.12.013